One of the first tasks on the to-do list for new Obama administration agency heads will be dealing with the midnight regulations left by the Bush administration. The White House has likely said all its going to say on the issue (more here), but the majority of Bush's regulations are still unaddressed.

California is once again seeking federal approval for its plans to regulate greenhouse gas emissions from vehicles. If the Environmental Protection Agency gives California the green light, 17 other states representing almost half of the U.S. auto market are expected to follow suit.

The Food and Drug Administration has made a controversial policy change that will allow pharmaceutical companies to market unapproved, or "off-label," uses of drugs. The policy, coming in the form of a guidance document, will allow industry representatives to use journal studies to persuade doctors to prescribe FDA-approved drugs for unapproved uses. More from Reuters:

Wednesday, Reg•Watch blogged about President Bush's decision to appoint Susan Dudley as the acting administrator of the Office of Information and Regulatory Affairs — the White House office in charge of clearing federal regulations. Dudley has been the administrator since 2007, but her recess appointment expired, forcing Bush to give her "acting" status.